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PIL - Simvastatin 10mg, 20mg, 40mg, 80mg film-coated tablets: Change history

  • B.II.b.1.b - QUALITY CHANGES - FINISHED PRODUCT - Manufacture - Replacement or addition of a manufacturing site for part or all of the manufacturing process of the finished product - Primary packaging site

    - addition of Accord Healthcare Single Member S.A., Greece as an alternative site responsible for primary packaging site.

    B.II.b.1.a - QUALITY CHANGES - FINISHED PRODUCT - Manufacture - Replacement or addition of a manufacturing site for part or all of the manufacturing process of the finished product - Secondary packaging site

    -addition of Accord Healthcare Single Member S.A., Greece as an alternative site responsible for secondary packaging site.

    B.II.b.2.c.2 - QUALITY CHANGES - FINISHED PRODUCT - Manufacture - Change to importer, batch release arrangements and quality control testing of the finished product - Replacement or addition of a manufacturer responsible for importation and/or batch release - Including batch control/testing

    -addition of Accord Healthcare Single Member S.A., Greece as an alternative site responsible for importation and batch release including batch control/testing.

    • Changes: (Updated: 30 Oct 2025)

      B.II.b.1.b - QUALITY CHANGES - FINISHED PRODUCT - Manufacture - Replacement or addition of a manufacturing site for part or all of the manufacturing process of the finished product - Primary packaging site

      - addition of Accord Healthcare Single Member S.A., Greece as an alternative site responsible for primary packaging site.

      B.II.b.1.a - QUALITY CHANGES - FINISHED PRODUCT - Manufacture - Replacement or addition of a manufacturing site for part or all of the manufacturing process of the finished product - Secondary packaging site

      -addition of Accord Healthcare Single Member S.A., Greece as an alternative site responsible for secondary packaging site.

      B.II.b.2.c.2 - QUALITY CHANGES - FINISHED PRODUCT - Manufacture - Change to importer, batch release arrangements and quality control testing of the finished product - Replacement or addition of a manufacturer responsible for importation and/or batch release - Including batch control/testing

      -addition of Accord Healthcare Single Member S.A., Greece as an alternative site responsible for importation and batch release including batch control/testing.

    • Changes: (Updated: 25 May 2023)

      Description of update: The following change has been notified:

      C.I.z Change(s) in the Summary of product Characteristics, Labelling or Package Leaflet intended to implement the outcome of a PRAC signal recommendation: implementation of wording agreed by the competent authority that do not require any further assessment

      - To update the SmPC and PIL to implement the signal recommendation (EPITT 19822) adopted at the 9-12 January 2023 PRAC meeting.

      PIL sections updated: 2, 4, 6.

    • Changes: (Updated: 09 Nov 2022)

      Updated

    • Changes: (Updated: 22 Sep 2022)

      Initial upload

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